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2022-RA-1557-ESGO Mesenteric lymph node involvement in patients undergoing a bowel resection during debulking surgery in advanced ovarian cancer
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  1. Federica Galli1,
  2. Giorgio Candotti1,
  3. Alessandro Ruffolo1,
  4. Maria Luisa Fais2,
  5. Patrizia de Marzi1,
  6. Michele Peiretti2,
  7. Enrico Erdas3,
  8. Stefano Angioni2,
  9. Giulia Sabetta1,
  10. Luca Bocciolone1 and
  11. Massimo Candiani1
  1. 1Obstetrics and Gynecology Unit, IRCCS San Raffaele Scientific Institute,Milan, Italy., Milan, Italy
  2. 2Department of Surgical Sciences, Division of Gynecology and Obstetrics, University of Cagliari, Italy., Cagliari, Italy
  3. 3Department of Surgical Sciences, University of Cagliari, Monserrato, CA, Italy, Monserrato, Italy

Abstract

Introduction/Background The aim of this retrospective study was to investigate the incidence of mesenteric lymph node (MLN) involvement in patients undergoing a bowel resection at the time of debulking surgery in advanced ovarian cancer (OC).

Methodology OC patients undergoing rectosigmoid resection during primary debulking surgery or interval debulking surgery were recorded. The characteristics of mesenteric node involvement were evaluated.

Results MLNs were detected in 29/54 patients (54%); the rate of MLN involvement was 61%. A progressive increase in the rate of metastatic MLNs was documented in association with depth of bowel infiltration (p=0.009). A statistic correlation between positive MLN and pelvic lymph nodes (PLN) (p=0.022), aortic lymph nodes (ALN) (p=0.005) was found.

Conclusion OC patients undergoing rectosigmoid resection during debulking surgery revealed metastatic MLN involvement in 61% of cases. Metastatic MLN status is related to PLN and ALN metastases.

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