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2022-RA-1235-ESGO Adult ovarian granulosa cell tumors: clinical and imaging findings characteristics of a Tunisian population sample
  1. Rahma Bouhmida,
  2. Nesrine Souayeh,
  3. Amal Chermiti,
  4. Hajer Bettaieb,
  5. Meriem Ouederni,
  6. Wael Mbarki,
  7. Idriss Abidi,
  8. Hadir Lamiri,
  9. Hadhami Rouiss,
  10. Hedhili Oueslati and
  11. Chaouki Mbarki
  1. Gynecology and obstetrics, Regional hospital ben Arous Tunisia, Tunis, Tunisia


Introduction/Background Adult-type granulosa cell tumor (GCT) is a rare subtype of ovarian cancer. It derlves from sex cord stromal cells of the ovary. The incidence of GCTs is 0.6–0.8/100,000, and it represents 3–5% of all ovarian malignancies.

Methodology a retrospective study concerning 40 cases of ovarian sex cord-stromal tumors (OSCST). Among them, we collected 17 cases of GCT. Epidemiological, clinical and radiological data were analyzed in this study.

Results GCT represented 42.5% of the OSCSTs and 1.15% of all ovarian tumors during the study period. The average age was 42.3 years . The mean parity of patients was 4. Menopausal average age calculated at 49 years . In 80% of cases patients were symptomatic; chronic pelvic pain 43.5%, meno-metrorrhagia 36.5%. For Three patients the tumor was discovered by chance: one during a caesarean scare and two during an ultrasonography for infertility. Physical exam revealed a palpable mass in 9 cases (52.9%). with an average size of 8 cm, and a solid consistency. On ultrasonography, we found a compartmentalized cystic tumor with vascularized partitions in color and pulse Doppler in 71.42% of cases . An effusion in the douglas has been described in 35.71% .The ultrasound study must incorporate the endometrium, in our study, the endometrium was hyperplastic in two cases. In CT we found a predominant cystic forms (53%) with variable contents .In MRI, in75% of cases we found a hyposignal with T2 weighting with a multilocular cystic appearance with solid components.

Conclusion The variability in the histological type globally and in the cellular arrangement particularly of granulosa tumors has helped to create a spectrum of radiological manifestations, whose good assimilation of their semiology will make it easier to pose the diagnosis before the surgery.

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