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Ovarian cancer
2022-RA-1215-ESGO The prognostic impact of Preoperative LMRof the body fluid in patients with epithelial ovarian cancer
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  1. Min J Jeong1 and
  2. Ji Su Mun2
  1. 1Obstetrics and Gynecology, Eunpyeong St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of
  2. 2Eunpyeong St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, Seoul, Korea, Republic of

Abstract

Introduction/Background The cumulative results indicate that the lymphocyte to monocyte ratio of serum (sLMR) is a useful prognostic factor in patients with various cancers. In contrast to peripheral blood, the body fluid is in direct contact with the pelvic lesion. However, no study has reported on the clinical utility of the LMR of body fluid (bLMR) for patients with epithelial ovarian cancer. To investigate the clinical utility of the bLMR as a prognostic factor in patients with ovarian cancer, we conducted a retrospective review of the prospectively collected data.

Methodology 92 patients with ovarian cancer treated in eight multicenter institutions over the last 20 years were retrospectively analyzed.

Results A multivariable analysis confirmed that histologic grade (p< 0.001), optimal debulking (p<0.001), serum LMR (p=o.oo7) and malignant body fluid LMR (p=0.006) were independent predictors of recurrence.

Abstract 2022-RA-1215-ESGO Figure 1
Abstract 2022-RA-1215-ESGO Figure 1

Conclusion Although further studies are required to apply our results clinically, this is the first study to show the clinical value of the bLMR in patients with epithelial ovarian cancer.

https://doi.org/10.1136/ijgc-2022-ESGO.662

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