Introduction/Background Ovarian granulosa cell tumors represent a particular subset of ovarian tumors characterized through a low rate of multiplication of the tumoral cells and a low risk of developing distant metastases. However, in isolated cases recurrences might develop.

Methodology The current paper presents the cases of two patients diagnosed with mesosigmoidian metastases from ovarian granulosa cell tumors.

Results The first case was investigated for diffuse abdominal pain after an incidental abdominal trauma while the second case was investigated for subocclusive syndrome. In the first case the preoperative suspicion of diagnostic was of a retroperitoneal hematoma while in the other case the preoperative suspicion of diagnostic was of peritoneal carcinomatosis. Intraoperatively in the first case a large ruptured recurrence with perilesional hematoma was found while in the second case a recurrent tumor at the level of the mesosigmoidian area, in close contact with the sigmoidian lumen was found. In both cases a rectosigmoidian resection was performed, the histopathological studies demonstrating the presence of mesosigmoidian recurrences.

Conclusion Although ovarian granulosa cell tumors usually exhibit a good prognostic and a low rate of recurrence, relapsed tumors with atypical locations might be found. In such cases different visceral resections might be needed in order to control the disease