Introduction/Background Endometrial cancer in Mexico represents the second place, followed by cervical cancer. High-risk staging and treatment involves total hysterectomy, bilateral salpingo-oophorectomy with pelvic and/or para-aortic lymphadenectomy. Surgical staging is necessary in high and intermediate risk cases to assess the extent of the disease and the need for adjuvant therapy, which is why it is important to know the lymph node status to assess the prognosis. Our objective is to evaluate whether para-aortic lymphadenectomy increases vascular lesions compared to pelvic lymphadenectomy in endometrial cancer in a cancer reference center in Mexico.

Methodology A retrospective analysis of 44 cases of endometrial cancer that had complete surgical staging was performed. Comparisons were analyzed using Student’s t-test and Mann-Whitney tests. For the statistical analysis, SPSS version 23 was used.

Results The surgeries were performed by experienced gynecologists or surgical oncologists. The median age was 53 years, in the analysis we could not identify statistical differences between the rest of the complications, the main complication was lymphocele with p: 0.03, between the pelvic lymph node dissection (PLND) group, compared with the group of PLND and para-aortic lymph node dissection (PALND), vascular injuries were not significant, as well as ureteral injury, reintervention, infection.

Conclusion PLND and PALND do not increase vascular lesions, however if the number of lymphoceles increases, our pelvic and para-aortic lymph node dissections are performed by experienced gynecologists or surgical oncologists with more than three years of surgical training in a national reference center, which could be an important factor, however, in this study we can conclude that vascular injuries do not increase when we perform para-ortic dissection.