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2022-VA-1045-ESGO Sentinel lymph node biopsy in surgical staging for endometrial carcinoma patients
  1. Laura Gil García,
  2. Ana Pérez-Cejuela,
  3. Alejandro Muller Bravo,
  4. Marina Pérez Duce,
  5. Patryk Daniel Janiszewski,
  6. María De Cardenas Carrillo de Albornoz,
  7. Ana María Granado San Miguel and
  8. Jose Antonio Mestanza Garrido
  1. Hospital General Universitario de Talavera de la Reina, Talavera de la Reina, Spain


Introduction/Background Sentinel lymph node mapping (SLN) has emerged as a reliable alternative for endometrial cancer (EC) lymph node assessment. Numerous studies have shown that SLN is comparable to LND in both low- and high-risk EC patients, and that oncological outcomes are similar between the SLN and LND groups (1, 2). The 2020 National Comprehensive Cancer Network guidelines (3) recommend surgical staging in low- and high-risk EC patients. The advantage of SLN lies in pathological superstaging, avoiding overtreatment and undertreatment.

We did retrospective single-center study, to evaluate the detection rate and diagnostic accuracy of the SLN procedure in predicting pathological iliac lymph node status in patients with early-stage endometrial cancer from 1 April 2020 to 1 February 2022.

Methodology SLN assessment using cervical injection with green indocyanine administered to the cervix (superficial 1–3 mm and deep 1–2 cm, 4 ml in total) and systematic dissection of pelvic lymph nodes in patients with FIGO stage I-II endometrial cancer. All lymph nodes were histiopathologically examined, and SLNs were serially negative predictive value (NPV) of sentinel lymph node biopsy.

Results Overall, 22 patients, SLN group (21, 95%), and LND group (11, 50%) allowing us to correlate the results of both techniques. SLN were positive in 6 cases (28.5%) and LND were positive in 80% of cases. SLN mapping showed high sensitivity of 100 % and negative predictive value of 100 %, in our results.

Abstract 2022-VA-1045-ESGO Table 1

Patient charecteristics

Conclusion The current evidence for SLN mapping versus LND was reviewed. (4, 5, 6, 7). Regardless of the surgical approach, SLN reduces blood loss during surgery. Further studies on operative time and complications are needed for further analysis. SLN mapping is more targeted for fewer lymph node dissections and more positive lymph node detection, even in high-risk patients. The utility of SLN does not imply adverse survival in EC patients.

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