Objectives Endometrial cancer is the second gynecologic cancer. The varying tumors profile from country to country and the difference in the means available in each country have raised the need for a country-specific guideline. We aim to Present the Tunisian guideline for endometrial cancer

Methods All relevant international and national scientific literature available from 2016 to 2021 was used to establish this guideline.

Results This guideline was made by the Gynecologic Oncology Multidisciplinary team of the National Cancer center. Three questions were asked. What is the actual state of the art?Could it be applied in our country? If not, can we adapt the guideline to our reality?. During the consensus, the panel tried to cope between the actual state of the art and the Tunisian Field reality. The main limitations were the Distant radiation appointment, the patient loss to follow up, and the non-systematic use of biological markers. The 2009 FIGO classification was used to stage our patients. For stage I disease, The ESMO 2016 risk classification was used. One preoperatory and composed of three levels of risks low, intermediate, and high risk. The other classification is post-operatory and comprises low, Intermediate, high-intermediate, and high-risk levels. Based on this Data and our country reality panel developed recommendations.

Conclusions A country-specific guideline based on the international state of the art is more effective to offer the best quality of care available to our patients. It would also point to the lack and what needs to be done to keep on improving the health system.