Objectives To estimate the prevalence of endometrial cancer in Uzbekistan over the last 3 years.

Methods We collected uterine cancer statistical indicators from official statistics in Uzbekistan for the years 2018–2020.

Results Analyzed data of uterina cancer (UC) in 2018–20 years showed that 641 (1.4), 640 (1,9) and 609 (1,8) UC patients were identified in the Republic, respectively. In 2018 year 315 patients were from the country - side. The patients were into stages as follows: I stage - 31.2%, II stage - 39.9%, III stage - 16.1%, IV - 5.3%. The mortality rate in 2018 was 0.7 (234 patients) and the 5-year survival rate consisted 47.3%. The patients were into stages as follows: I stage - 34.8%, II stage - 41.7%, III stage - 14.4%, IV stage - 3.1%. The mortality rate in 2020 was 0.8 (256 patients) and the 5-year survival rate consisted 49.5%. In 2020 the patients were into stages as follows: I stage – 35,8%, II stage – 41,7%, III stage – 11,3%, IV stage – 4,4%. 568 patients were from the country-side. 5-year survival rate consisted 48,7%. The mortality rate in 2020 was 0,8 (274).

Conclusions The morbidity of UC in Uzbekistan has not tend to decrease and requires primary care physicians to promote a healthy lifestyle, a more careful approach to all types of uterine bleeding at women of both fertile and menopausal age. Timely putting diagnosis and treatment of endometrial hyperplastic processes will significantly reduce the number of women at risk for UC.