Objectives The objective of this study is to determine the clinical characteristics, treatment response and prognosis of locally advanced adenocarcinoma of the cervix who underwent concurrent chemoradiotherapy with weekly Cisplatin or Carboplatin in comparison to squamous cell carcinoma.
Methods Outpatient charts of the cervical cancer patients from the outpatient department of Section of Gynecologic Oncology of a tertiary hospital were retrospectively reviewed.
Results Among the 979 charts reviewed, only 278 patients were included in the analysis. Seventy-five percent of the patients had squamous cell carcinoma and only 20% had adenocarcinoma. Baseline characteristics were comparable. Ninety-eight percent had Cisplatin-based concurrent chemoradiotherapy. Median follow up was 17 months, with 75% of the patients had complete response and 16% had recurrent disease. Most common site of recurrence was cervix, lungs and bones. Disease free survival and overall survival was the same for adenocarcinoma and squamous cell carcinoma.
Conclusions Patients with locally advanced adenocarcinoma of the cervix who underwent concurrent chemoradiation had the same treatment response and prognosis to patients with squamous cell carcinoma.
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