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EPV090/#629 Patterns of care and outcomes of adenocarcinoma of cervical cancer post treatment – retrospective study from a tertiary care centre in South India
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  1. JK Ramireddy1,
  2. N Oliver John1,
  3. A Sathyamurthy1,
  4. J Priyadarshini Rao1,
  5. S Milton1,
  6. V Thomas1,
  7. A Thomas2 and
  8. T Ram1
  1. 1Christian Medical College and Hospital, Vellore, Department of Radiation Oncology, Vellore, India
  2. 2Christian Medical College, Vellore, Gynecologic Oncology, Vellore, India

Abstract

Objectives Non - squamous histologies such as adenocarcinoma of the cervix might have an aggressive clinical course. There is sparse literature on tailoring treatment in adenocarcinoma cervix. In this study we plan to do a retrospective review of patients with this entity.

Methods The medical records of 2462 patients with cervical cancer between January 2008 to December 2018 were collected. The records of 180 patients who had histologically proven adenocarcinoma cervix were reviewed. The demographics, treatment modalities and outcomes were analyzed in 111 patients who had treatment in this institution.

Results The mean age of the patients was 57.52 years (Range 20–84 years). Demographics and treatment details are presented in the attached table (table 1).The median follow up period was 20 months. The median overall survival in stage 1, stage 2, stage 3 and stage 4 are 37(IQR:17–60), 28(IQR: 12.5 -40.5), 11.5(IQR:7–34) and 9 (IQR:5–16) months respectively. The median survival for the entire cohort was 22 months (IQR : 9–48).

Abstract EPV090/#629 Table 1

Patient details

Conclusions This present study shows poorer survival when compared to squamous cell carcinoma in literature. The benefit of addition of chemotherapy or surgery as salvage to the present standard of care needs to be studied prospectively in a larger population.

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