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EPV042/#199 Racial and regional disparities in the diagnosis of advanced stage cervical cancers in the US: who is most at risk?
  1. C-I Liao1,
  2. A Francoeur2,
  3. D Wong2,
  4. A Mann3,
  5. MA Caesar4,
  6. A Chan5,
  7. B Monk6,
  8. D Kapp7 and
  9. J Chan8
  1. 1Kaohsiung Veterans General Hospital, Obstetrics and Gynecology, Kaohsiung City, Taiwan
  2. 2University of California Los Angeles, Obstetrics and Gynecology, Los Angeles, USA
  3. 3Palo Alto Medical Foundation, Research Institute, Palo Alto, USA
  4. 4California Pacific Medical Center, Research Institute, San Francisco, USA
  5. 5Palo Alto Medical Foundation Research Intitute, Obstetrics and Gynecology, Palo Alto, USA
  6. 6Arizona Oncology, Gynecologic Oncology, Obstetrics and Gynecology, Phoenix, USA
  7. 7Stanford University School of Medicine, Department of Radiation Oncology, Stanford, USA
  8. 8California Pacific Medical Center, Obstetrics and Gynecology, San Francisco, USA


Objectives Prior studies have found an increase in advanced stage cervical cancers in the US. We propose to determine the high risk group based on demographic and clinical characteristics.

Methods Microscopic confirmed cervical cancer was obtained from United States Cancer Statistics (USCS) from 2001 to 2017. Age-adjusted incidence (AAI, per 100,000 women, corrected by US 2000 standard population), age-specific incidence (ASI, per 100,000 women), and trends were calculated by SEER*Stat 8.3.8 and Joinpoint Regression Program

Results Of 27,102 patients with advanced stage cervical cancer from 2001–2017, 17,097 (63%) were White, 4,939 (5%) were Black, 3,636 were Hispanic (2%), and 1,117 were Asian (0.5%). Squamous and adenocarcinoma consists of 17,867 and 4,992 patients, respectively. The age group with the highest incidence of advanced cancer was 50–54 years, 2.29/100,000. Based on race, Black and Hispanic patients have higher incidence at 1.35/100,000 and 1.18/100,000 compared to White patients, 0.86/100,000. With respect to region, the South has the greatest incidence at 1.04/100,000. The intersectionality of age, race and region finds that Black women, aged 65–69, residing in the South have the highest incidence at 4.19/100,000, an incidence nearly three times higher than White women of the same age in the South at only 1.63/100,000.

Conclusions Advanced stage cervical cancer continues to disproportionately affect minorities in Southern regions in the US. Resources toward screening and vaccination are needed in these at risk groups.

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