Objectives To investigate pregnancy outcomes in women after radical trachelectomy (RT) in KazIOR for early-stage cervical cancer
Methods Systematic analysis of the data of the cancer register of the Republic of Kazakhstan
Results Since 2013, radical trachelectomy has been performed at KazIOR. From 2013 to 2021, 8 operations were performed, 7 of them by abdominal access, 3 by laparoscopic approach. 6 (75%) of the patients had stage 1 B1 from 2 to 4 cm; 2 (25%) had a 1a1 stage.The average age of patients was 28 years (from 26 to 37 years). 5 (62.5%) patients were nulliparous, 2 patients had 2 children, 1 patient had 1 child.
LVSI was negative in preoperative histological examination, and resection margins were also negative. The histological form of the tumor in all cases was squamous cell carcinoma. On average, 11 lymph nodes were removed. In 1 patient (12.5%) after histological examination LVSI was positive, in 7 it was negative. None of the patients had metastases to the pelvic lymph nodes. During express histology, the resection margins were negative in all patients. Patients in the postoperative period were not prescribed chemoradiation therapy. of the 8 patients who retained fertility, there were 5 pregnancies, 2 miscarriages at 9–10 weeks, and 3 deliveries at 36–37 weeks of gestation.
Conclusions Thus, in 2013–2021, 8 radical trachelectomy operations were successfully performed. The data presented in this publication demonstrate that patients with stage IB1 tumors ranging in size from 2 to 4 cm and with favorable histology are acceptable candidates for attempted radical trachelectomy.
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