Objectives The aims of this study were to report nutritional status in 19 patients with cancer requiring neoadjuvant chemotherapy and to study the influence of nutritional status on their quality of life.

Methods It is a retrospective study included 19 patients t who received neaoadjuvant chemotherapy between 2015 and 2019 at salah azaiez institute Tunisia., we collected the nutritional status (weight, anorexia grading, type of diet),socociodemographics (age, gender, and marital status); tumor: localization, staging; health status (performance status according to WHO classification, usual weight and body mass index (BMI).

Results Between 2015 and 2019, 19 patients were included. The median age was 52 years (ranging 30–72). All patients had breast cancer and received neoadjuvant chemotherapy. 13 patients were menopaused, two patients were diabetic, 14 patients had high blood pressure and 4 had dyslipidemia. BMI was normal in 6 cases, overweight in 4 cases and obesity in 9 cases. The majority of the tumor were classified T4B. 17 patients had invasive ductal carcinoma. During chemotherapy,3 patients follow vegetables and fruit diets, 7 follow mixed diets and 9 follow western diet.Three patient had a sport activity, sedentary lifestyle was noted in 9 patients et 7 patients had a normal daily activity. The evaluation of the response based on imaging firstly and histological examination.

Conclusions The nutritional status of patients with cancer requiring neaoadjuvant chemotherapy was relatively preserved. Functional impairment, the presence of anorexia, appear to be independent predictive factors of quality of life in patients who will recivied neaoadjuvant chemotherapy.