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EPV270/#88 Optimizing the screening and management of preoperative anemia prior to gynecologic oncology surgery (OPRA): a quality improvement initiative
  1. E Spenard1,
  2. Y Lin2,
  3. A Covens3,
  4. L Gien3,
  5. J Callum2,
  6. R Tano2,
  7. S Jadunandan2,
  8. P Trbovich4 and
  9. D Vicus3
  1. 1University of Toronto, Gynecologic Oncology, Toronto, Canada
  2. 2Sunnybrook Health Sciences Center, Laboratory Medicine and Molecular Diagnostics, Toronto, Canada
  3. 3Sunnybrook Health Sciences Centre, Gynecologic Oncology, Toronto, Canada
  4. 4University of Toronto, Institute of Health Policy, Management and Evaluation, Toronto, Canada


Objectives Preoperative anemia is an established negative prognostic factor in gynecologic oncology patients. However, it is often undetected and inadequately treated. The aim of this quality-improvement initiative was to increase the treatment rate of preoperative anemia in gynecologic oncology patients undergoing surgery at a large tertiary centre.

Methods This was a time-series study between October 1, 2019-April 1, 2021. All gynecologic oncology patients consented for surgery at our institution were included. From October to December 2020, three interventions were implemented: a tracking system for patients consented for surgery, standardized screening for preoperative anemia, and automatic referral to patient blood management program(PBMP). The primary outcome was the treatment rate of patients with anemia receiving intravenous iron or erythropoiesis-stimulating agent prior to surgery. Secondary outcomes were perioperative blood transfusion rate, postoperative nadir hemoglobin(Hb) level and length of stay(LOS). Process measures included screening and PBMP referral rates. Balancing measures included treatment complications and patient satisfaction.

Results of the 151 pre-intervention and 229 post-intervention patients, 32%(n=121) had anemia. After intervention, screening rates and PBMP referral rates increased from 2% to 82%(p<0.00001) and 9% to 80%(p<0.00001), respectively. The treatment rate increased from 7% to 31%(p<0.009). The transfusion rate decreased from 20% to 12%(p=0.027). The postoperative nadir Hb level increased from 92 to 96g/L(p=0.049). There was no difference in LOS across all surgeries. No treatment associated complications were reported. The median patient satisfaction score was 4.5 on a five-point Likert scale.

Conclusions Optimizing treatment of preoperative anemia in gynecologic oncology patients significantly decreased transfusion rate, without affecting LOS.

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