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EPV233/#102 Comparison of localized and intravenous analgesia treatment in women undergoing L.L.E.T.Z under general anesthesia
  1. G Haran1,
  2. I Fainberg2,
  3. D Millatiner2,
  4. Y Vinnikov2 and
  5. S Bochobza2
  1. 1Tel Aviv University, Medicine Faculty, Tel Aviv, Israel
  2. 2Maayanei HaYeshua Medical Center, Gyn-Onc Unit, Benei Brak, Israel


Objectives Conization is currently performed under general anesthesia with IV analgesia or without anastesia, with local analgesia injected to the cervix. Woelber & co compared the incidence and intensity of pain after conization under general/local anesthesia and found no significant differences. No study has compared the effect of analgesia administered via IV or local routh. This study aim to determin pain&bleeding rate when undergoing conization, depending on routh of analgesia.

Methods A prospective blind-control study comparing 30 women undergoing cervical conization under general anastesia in our hospital between 2019–2020. 15 women (A) were administered intravenous analgesia, and 15 women (B) were administered local analgesia injection to cervix. Chi-Square test was used to find the group diffrences.

Results From 30 patients recruited, 14 left in group A and 15 in group B. No demographics differences were found. Extra analgesia in the 24 hours post-Op was found in14.3%(A) and 28.6% (B) (p-value <0.05). Most reported no pain in the first hour after conization, with the pick of pain appearing 4–8 (A) and 8–12 (B) hours after conization. Amount of intra-op bleeding was <100 ml in 21.4% (A) and 80%(B) (p-value=0.003). Post-conization bleeding was <100ml in 42.9% (A) and 71.4% (B) with no statistical significancy. One patient from group B needed hemostasis intervention 3 weeks after conization.

Conclusions Conization of the cervix under local analgesia is as effective in pain prevention as general analgetica and reduce the amount of bleeding during and possibly after the operation. More resurch is needed to conclude the preferred routh of analgesia.

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