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EPV202/#446 Sentinel lymph node identification in early stage ovarian cancer: is it still possible after prior tumor resection?
  1. P Laven1,
  2. R Kruitwagen2,
  3. S Lambrechts2,
  4. T Van Gorp3,
  5. B Slangen4,
  6. P Zusterzeel5 and
  7. J Van Der Pol6
  1. 1Maastricht Universitair Medisch Centrum, Gynaecology, Maastricht, Netherlands
  2. 2Maastricht University Medical Centre, Gynecology, Maastricht, Netherlands
  3. 3University Hospital Leuven, Gynaecological Oncology, Leuven, Belgium
  4. 4Maastricht University Medical Center, Gynaecology and Obstetrics, Maastricht, Netherlands
  5. 5Radboud Univeristy Hospital, Gynaecological Oncology, Nijmegen, Netherlands
  6. 6Maastricht Universitair Medisch Centrum, Nuclear Medicine, Maastricht, Netherlands


Objectives Sentinel lymph node (SLN) detection in ovarian cancer is feasible when tracers are injected before the pathological ovary is resected. This study aims to investigate whether the SLN identification is also feasible in patients whose ovarian tumor has already been resected with injection of the tracer into the ovarian ligaments stumps, i.e. in the event that a frozen section confirms malignancy.

Methods Patients who underwent laparotomy with frozen section confirming an ovarian malignancy, and those who underwent a second staging laparotomy after prior resection of a malignant ovarian mass, were included. Blue dye and a radioactive isotope were injected in the stumps of the ligamentum ovarium proprium and the ligamentum infundibulo-pelvicum. After an interval of at least 15-minutes, the sentinel node(s) were identified using either the gamma-probe and/or blue dye.

Results A total of 11 patients were included in the study, the sentinel node (SLN) procedure was completed in all 11 patients. At least one SLN was identified in 3 patients, resulting in a rather low detection rate of 27,3%.

Conclusions In this study we showed that SLN procedure after (previous) resection of the tumor seems inferior to detect sentinel nodes when compared to injection of the tracer in the ovarian ligaments before tumor resection.

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