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410 Long-term outcome in endometrial cancer patients after robot-assisted laparoscopic surgery with sentinel lymph node mapping
  1. NJ Nordskar1;2,
  2. B Hagen2,
  3. S Tingulstad2,
  4. EV Vesterfjell3,
  5. Ø Salvesen4 and
  6. G Aune1;2
  1. 1Norwegian University of Science and Technology, Department of Clinical and Molecular Medicine, Trondheim, Norway
  2. 2St Olavs hospital, Trondheim University hospital, Department of Gynecologic Oncology, Trondheim, Norway
  3. 3St Olavs hospital, Trondheim University hospital, Department of Pathology, Trondheim, Norway
  4. 4Unit of Applied Clinical Research , Department of Public Health and Nursing, Trondheim, Norway


Introduction/Background*The aim was to provide long-term outcome data in endometrial cancer patients undergoing robot-assisted laparoscopic surgery and sentinel lymph node (SLN) mapping.

Methodology Retrospective cohort study of 108 patients with primary endometrial cancer who underwent robot-assisted laparoscopic surgery and sentinel lymph node mapping using the Memorial Sloan Kettering Cancer Center algorithm with near-infrared fluorescence detection of indocyanine green for endometrial cancer from November 20th 2012 to January 1st 2016 at St. Olavs hospital in Norway. The primary endpoint was recurrence-free survival. Secondary endpoints were overall survival and treatment complications.

Result(s)*After a median follow up of 75 months (range 61-98), five (4.6%) patients had recurred and three patients had died from the disease. The 5-year recurrence-free survival was 95.4% (95% CI, 91.5 – 99.3). The 5-year disease specific survival was 97.2% (95% CI, 94.1 – 100.3). Four of the patients with recurrent disease had lymph node metastasis at diagnosis. The 5-year overall survival was 92.6% (95% CI, 87.7 – 97.5). Peripheral neuropathy after chemotherapy was the most common complication (9.3%), followed by lower limb edema (2%) and postoperative hernia (2%).

Conclusion*The present study demonstrated excellent oncologic outcome and few treatment complications in patients treated according to the SLN algorithm more than five years after diagnosis.

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