Introduction/Background*Bone metastases of gynecological cancer are rare. To complete the initial staging of the disease, a combination of BS (bone scan) and CT (computerized tomography scan) is essential considering the unavailability of PET scan (positron emission tomography).
The aim of this study is to explore the bone involvement of gynecological cancer.
Methodology It is a retrospective study including gynecological cancer patients, referred for bone scan during 2019, at the Nuclear Medicine department of Tlemcen University Hospital in Algeria.
Two hours after the intravenous injection of 8-10 MBq/kg 99mTc-HMDP (hydroxy methylene diphosphonate), whole body scanning is accomplished by dual head hybrid gamma camera with low energy high resolution collimator.
Result(s)*Twenty-three bone scans were indicated in the initial staging of gynecological cancer patients, median age of 59 years [42-81], to explore bone pain in 15 cases (65%) or an advanced stage of the neoplasms (peritoneal carcinomatosis, bone metastases or lung metastases) in 08 cases (35%).
The different types of tumors are ovarian (10; 43,5%), cervical (9; 39,1%), and endometrial (4; 17,4%).
The majority of BS (15 patients; 65,2%) are relevant of osteoarthritis, involving both the spine and the peripheral joints, which are symptomatic in knees and shoulders. 4 patients (17,4%) had normal scintigraphy.
Four patients (17,4%) had multiple bone metastases with hot uptake scintigraphic pattern, involving both the axial and appendicular skeleton. Among these cases, the most common metastatic sites are pelvis, spine, and rib. Upon these metastatic patterns, 2 cases are related to endometrial cancer (8,7%), the rest are related to cervical (1; 4,34%) and ovarian carcinoma (1; 4,34%). Bone pain was present in 3 metastatic cases involving spine, the rest was declared with bone metastases at CT.
Conclusion*Bone involvement of gynecological cancer is not frequent, it can be symptomatic or reported by CT scan. BS is a useful tool to explore with its good sensitivity the entire skeleton, in order to stage the neoplasm.
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