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5 Comparison of localized and intravenous analgesia treatment in women undergoing L.L.E.T.Z under general anesthesia
  1. G Haran1,2,
  2. I Fainberg3,
  3. D Millatiner3,
  4. J Lessing3,
  5. S Assarafh3,
  6. Y Vinikov3 and
  7. S Bukovza3
  1. 1Tel Aviv University, Tel Aviv-Yafo, Israel
  2. 2Mayanei HaYeshua Medical Center, Gynecological Oncology Unit, Bnei Brak, Israel
  3. 3Mayanei HaYeshua Medical Center, Bnei Brak, Israel


Introduction/Background*Conization is the act of choice for the treatment of pre-malignant lesions of the cervix, enabeling histological diagnosis and the treatment of premelignant and stage 1a1 tumors. Conization is currently performed under general anesthesia with IV analgesia or without anastesia, with local analgesia injected to the cervix.

Woelber & co compared the incidence and intensity of pain after conization under general or local anesthesia and found no significant differences. No study has compared the effect of analgesia administered via IV or local routh. The purpose of this study was to determin the pain rating and bleeding when undergoing conization, depending on the routh of analgesia.

Methodology A prospective blind-control study comparing 30 women undergoing cervical conization under general anastesia in our hospital between 2019-2020. First 15 women (A) were administered intravenous analgesia, and second 15 women (B) addmited were administered local analgesia injection to cervix. Chi-Square test was used to find the group diffrences.

Result(s)*From 30 patients recruited, one fell choosing only local anastesia, leaving 14 in group A and 15 in group B. No demographics differences were found. Extra need of analgesia in the 24 hours post-Op was found in14.3%(A) and 28.6% (B) (p-value <0.05). Most reported no pain in the first hour after conization, with the pick of pain appearing 4-8 (A) and 8-12 (B) hours after conization. Amount of intra-op bleeding was <100 ml in 21.4% (A) and 80%(B) (p-value=0.003). Post-conization bleeding was <100ml in 42.9% (A) and 71.4% (B) with no statistical significancy. One patient from group B needed hemostasis intervention 3 weeks after conization.

Abstract 5 Table 1

Pain intensity by hours, n(%)

Abstract 5 Table 2

Intraoperative and postoperative bleeding

Conclusion*Conization of the cervix under local analgesia is as effective in pain prevention as general analgetica and reduce the amount of bleeding during and possibly after the operation. More resurch is needed to conclude the preferred routh of analgesia.

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