Article Text

Download PDFPDF

550 Diagnostic and therapeutic approaches for patients with a STIC lesion – results of the AGO ovar questionnaire based survey in Germany
  1. J Van der Ven1,
  2. V Linz1,
  3. S Krajnak1,
  4. K Anic1,
  5. R Schwab1,
  6. S Kommoss2,
  7. B Schmalfeldt3,
  8. J Sehouli4,
  9. A Hasenburg1 and
  10. M Battista1
  1. 1Unimedizin Mainz, Klinik und Poliklinik für Geburtshilfe und Frauengesundheit
  2. 2Universitätsklinikum Tübingen, Department für Frauengesundheit
  3. 3Universitätsklinikum Hamburg-Eppendorf, Klinik und Poliklinik für Gynäkologie
  4. 4Charité Berlin, Klinik für Gynäkologie mit Zentrum für onkologische Chirurgie


Introduction/Background*Despite growing understanding of the carcinogenesis of high-grade serous ovarian cancer and its precursor lesion serous tubal intraepithelial carcinoma (STIC), there is a lack of evidence based recommendations for the clinical management of patients with a STIC lesion.

Methodology We created 23 questions to explore the experience with STIC patients and the diagnostical, surgical and histopathological approaches and used SoSci Survey to host the questionnaire. We invited all German directors of gynecological departments to participate.

Result(s)*550 colleagues were invited. 131 questionnaires (response rate 24.3%) were returned and included in this survey. 45.8% of the respondents treated one to three STIC patients. 76.0% of the participants performed opportunistic bilateral salpingectomies during other gynecological interventions. Most of the participants requested the SEE-FIM protocol from their pathologists since 2017. It was used by 54.2% for prophylactic salpingectomies, by 28.1% for both prophylactic and opportunistic salpingectomies and by 17.7% for neither of both. In a case of a STIC lesion 58.8%, 2.4%, 37.6% of participants used the laparoscopic, transvers- or longitudinal laparotomic approach, respectively. The respondents performed a hysterectomy, bilateral ovarectomy or affected side ovarectomy in pre- and postmenopausal patients in 25.6% (54.6%), 24.42 (88.4%) and 50.0% (4.6%), respectively (all p-values >0.001). Omentectomy, pelvic and para-aortic lymphadenectomy were performed in pre- and postmenopausal women in 60.5% (63.9%), 9.30% (11.6%) and 9.3% (11.6%) (all p-values <0.05).

Conclusion*This survey highlights significant inconsistency in the management of patients with a STIC lesion. Further studies are urgently warranted to elucidate the clinical impact and the necessary therapeutic approach of STIC lesions.

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.