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1158 Prevalence of endometrial carcinoma in women with myoma uteri associated abnormal uterine bleeding (AUB) in a tertiary government hospital
  1. JL Tanchuling
  1. East Avenue Medical Center, Obstetrics and Gynecology, Quezon , Philippines


Introduction/Background*Myomas are the most common benign neoplasm of the female reproductive organs. They most commonly cause abnormal uterine bleeding (AUB) which is also manifestation of endometrial carcinoma. These two conditions can co-exist due to their sensitivity to estrogenic stimulation. This association, as reported in few reported articles, was also reproduced in this paper.

Methodology The study was a cross sectional retrospective in nature, which involves patients diagnosed with any kind of uterine fibroids presenting with abnormal uterine bleeding that were subjected to hysterectomy at a tertiary hospital from January 2015 – October 2019. A total of 284 recorded, eligible post hysterectomy cases were included.

Result(s)*This retrospective cohort study shows that the prevalence of endometrial carcinoma among Filipino women with myoma uteri associated AUB which equates to 11% (n= 31). Types 2 & 3 fibroid were associated with endometrial carcinoma,and were found to have the highest incidence of 68.75% and 48.89%. The higher the age, and presence of intermenstrual bleeding are strongly associated with the development of endometrial carcinoma among patients with myoma uteri each with a p value of <0.05.

Abstract 1158 Table 1

Factors associated with endometrial carcinoma among myoma uteri patients

Conclusion*Evaluation of endometrium in patients with increasing post menopausal age, hypertension and intermenstrual bleeding before performing hysterectomy for patients with myoma uteri associated bleeding is a must to avoid inadequate surgical treatment

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