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339 Rhabdomyosarcoma of the cervix in teenagers – is fertility preservation a feasible option?
  1. Felicia Elena Buruiana1,
  2. Bindiya Gupta2 and
  3. Kavita Singh1
  1. 1PanBirmingham Gynaecological Cancer Centre, Birmingham City Hospital; Gynaecological Oncology, Birmingham, UK
  2. 2The Pan-Birmingham Gynaecological Oncology Centre, City Hospital; PanBirmingham Gynaecological Cancer Centre, Birmingham City Hospital; Gynaecological Oncology, Birmingham, UK


Introduction/Background Embryonal rhabdomyosarcoma (RMS) of the cervix is a rare entity, encountered mainly in the first two decades of life. The literature consists mainly of case reports and few small case series, and no standard treatment guidelines are available. As this is a disease of adolescence, fertility preservation in well selected cases is of paramount importance.

Methodology We report 3 cases of embryonal RMS of the cervix in adolescents, along with their clinical presentation, histopathological features, diagnosis, management tailored to individual cases.

Results To date, two of the patients have been followed for 5 years and the remaining 1 for 2 years.

They all remained asymptomatic, with no evidence of recurrent disease on clinical examination and MRI.

Conclusion The embryonal type of cervical RMS is the most frequent type in this age group. Cervical RMS have good prognosis as usually they present early due to clinical features of bleeding or a mass protruding through the vagina. It should be considered as differential diagnosis for continuous vaginal bleeding in a teenager and should be investigated appropriately. The patients diagnosed with RMS should be managed by multidisciplinary team at cancer centre for best outcomes. Given the young age at diagnosis, fertility sparing treatment maintaining the oncological safety is of paramount importance and is associated with long term survival.

Disclosures Nil to disclose.

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