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236 Tumor size as independent prognostic factor in stage IA endometrioid endometrial adenocarcinoma
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  1. G Co and
  2. R Sicam
  1. University of the Philippines-Philippine General Hospital, Department of Obstetrics and Gynecology, Division of Gynecologic Oncology, Philippines

Abstract

Introduction To evaluate the effect of tumor size on the rate of recurrence among patients with stage IA endometrioid endometrial cancer.

Methodology This is a 10-year retrospective cohort study. Patients diagnosed with endometrioid endometrial adenocarcinoma stage IA managed surgically (peritoneal fluid cytology, extrafascial hysterectomy with bilateral salpingooophorectomy with bilateral pelvic lymph node dissection and para-aortic lymph node sampling) were included. Data extracted from the outpatient department weekly census of the Philippine General Hospital between January 1, 2008 to August 31, 2018 were obtained. Tumor size, clinico-pathologic factors, incidence of tumor recurrence were determined. Data analysis was carried out using Stata 14. Descriptive statistics such as mean, median, standard deviation were used for numerical data variables, while frequency and percentage were used for categorical variables. Kaplan-Meier method was used to determine survival curves between the 2 tumor size groups. A P-value of < 0.05 was significant.

Results Included in the study were 286 patients whose ages ranged from 22 to 76 years. Eleven patients (3.8%) had tumor recurrence. Tumor size was not significantly associated with increased risk of tumor recurrence.

Conclusion Data suggests that tumor size in itself did not increase tumor recurrence.

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