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Assessment of poor functional status and post-acute care needs following primary ovarian cancer debulking surgery
  1. Allison Grace Roy1,
  2. Colleen M Brensinger2,
  3. Nawar Latif1,
  4. Robert Giuntoli1,
  5. Sarah Kim1,
  6. Mark Morgan1 and
  7. Emily M Ko1
  1. 1 Division of Gynecologic Oncology, Penn Medicine, Philadelphia, Pennsylvania, USA
  2. 2 University of Pennsylvania Perelman School of Medicine, Philadelphia, Pennsylvania, USA
  1. Correspondence to Dr Allison Grace Roy, Obstetrics and Gynecology, University of Pennsylvania, Philadelphia, PA 19104, USA; allison.roy{at}pennmedicine.upenn.edu

Abstract

Introduction Poor baseline functional status is associated with adverse surgical outcomes. Additionally, decline in the postoperative setting may result in the delay of additional treatments, impacting overall survival. This study assesses the incidence and risk factors for functional decline following primary ovarian cancer debulking surgery in previously independent women using discharge location as a surrogate.

Methods All patients with a postoperative diagnosis of ovarian cancer who underwent surgical debulking and had documentation of discharge location were identified using the 2011–2012 American College of Surgeons National Surgical Quality Improvement Program database. Patients were excluded if their baseline functional status was dependent or partially dependent, or if they died before discharge. Discharge destination was dichotomized as home versus non-home. Descriptive data included demographics, comorbidities, and perioperative outcomes. Multivariable logistic regression was used to evaluate the association of clinical and surgical factors on discharge destination.

Results 1786 patients met the criteria for analysis; 120 (6.7%) patients were discharged to non-home. Differences between home and non-home discharges included age (53.2% vs 83.3% ≥60), body mass index (26.5 vs 27.8 median), comorbidities (45.2% vs 64.2% with ≥1), and complications (8.6% vs 30.0% with ≥1, all p<0.05). In multivariable logistic regression analyses, only increasing age and complications were independently associated with discharge to non-home. Those age ≥70 had 9.0 times the risk (95% CI 3.5 to 23.4; p<0.001) as age <50. The presence of one or more postoperative complications carried 4.5 times (95% CI 2.9 to 7.0; p<0.001) the risk of those without complications. 30 day mortality was also increased in patients discharged to non-home.

Discussion 6.7% of previously independent ovarian cancer patients were discharged to non-home following surgery. Major risk factors for non-home include older age, comorbidities, and postoperative complications. Efforts to optimize baseline functional status and minimize surgical complications may improve discharge rates to non-home and postoperative functional status.

  • ovarian cancer
  • postoperative complications
  • postoperative care
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Footnotes

  • Contributors AGR developed the study concept, performed data analysis, and wrote the manuscript. CMB assisted in statistical design and data analysis. EMK developed the study concept, assisted in statistical design and data analysis, and preparation of the manuscript draft. All authors assisted with manuscript editing and final review.

  • Funding Supported in part by Grant 124268-IRG-78-002-35-IRG from the American Cancer Society and by the George and Emily McMichael Harrison Fund, Penn Presbyterian Harrison Fund of the University of Pennsylvania Hospital Obstetrics and Gynecology Department.

  • Competing interests None declared.

  • Patient consent for publication Not required.

  • Provenance and peer review Not commissioned; externally peer reviewed.

  • Data availability statement Data may be obtained from a third party and are not publicly available.

  • Author note The project was reviewed by the Institutional Review Board at the University of Pennsylvania and determined that the proposal met eligibility criteria for IRB review exemption.

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