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  • Radical vulvectomy and groin node dissection in a patient with chronic neutropenia—maintenance of leucocyte count using granulocyte colony-stimulating factor

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Radical vulvectomy and groin node dissection in a patient with chronic neutropenia—maintenance of leucocyte count using granulocyte colony-stimulating factor
  1. D. W.G. Beynon,
  2. A Lopes,
  3. B. Daras and
  4. J. M. Monaghan
  1. Northern Regional Department of Gynaecological Oncology, Queen Elizabeth Hospital, Gateshead, Tyne and Wear, UK
  1. Address for correspondence: Mr J. M. Monaghan, Director, Northern Regional Department of Gynaecological Oncology, Queen Elizabeth Hospital, Sheriff Hill, Gateshead, Tyne and Wear, NE9 6SX, UK.

Abstract

A patient was referred for consideration of radical surgery in the presence of chronic neutropenia. We report the successful maintenance of an adequate neutrophil count during the perioperative period using Granulocyte colony-stimulating factor (GCSF), resulting in successful primary healing of the wounds in the absence of infective complications. The use of GCSF in gynecology is briefly reviewed.

  • chronic neutropenia
  • GCSF
  • vulval cancer.

https://doi.org/10.1046/j.1525-1438.1993.03060405.x

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