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Ovarian Sertoli-Leydig cell tumor: success with salvage therapy
  1. M. A. FINAN*,
  2. W. S. ROBERTS* and
  1. *Division of Gynecologic Oncology, H. Lee Moffitt Cancer Center and Research Institute at the University of South Florida, Tampa, Florida
  2. Division of Medicine, M.D. Anderson Hospital and Tumor Institute, Houston, Texas, USA
  1. Address for correspondence: Michael A. Finan, MD, Division of Gynecologic Oncology, Ochsner Clinic, 1514 Jefferson Highway, New Orleans, LA 70121, USA.


A case of metastatic ovarian Sertoli-Leydig cell tumor is presented. The patient achieved a complete pathologic response with four courses of cisplatin, vinblastine and bleomycin chemotherapy. Recurrence of the tumor was detected with elevated serum alpha-fetoprotein. After surgical debulking, the recurrence was treated with intra-arterial cisplatin and intravenous etoposide with pelvic radiation therapy followed by intravenous doxorubicin and cyclophosphamide. The patient is alive and disease free 75 months after initial diagnosis, 4 years after salvage therapy.

  • chemotherpy
  • ovarian
  • Sertoli-Leydig tumor

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