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P70 Description of the surgical management of patients with uterine corpus cancers in Belgium: results from a multicentric prospective observational study (EFFECT)
  1. A Kakkos1,
  2. A De Geyndt2,
  3. G Silversmit2,
  4. G Bouche3,
  5. E de Jonge4,
  6. G Jacomen5,
  7. H Denys6,
  8. E Van Limbergen7,
  9. B Vandermeersch8,
  10. J Kerger9,
  11. D Vander Steichel10,
  12. M Baldewijns11,
  13. E Lauwers12,
  14. N Van Damme2,
  15. F Goffin1 and
  16. F Amant7
  1. 1Gynecologic Oncology, CHU de Liège, Liège
  2. 2Belgian Cancer Registry
  3. 3Anticancer Fund, Brussels
  4. 4Gynecology-Obstetrics, Ziekenhuis Oost-Limburg, Genk
  5. 5Anatomopathology, AZ Sint-Maarten, Duffel
  6. 6Medical Oncology, University Hospital Ghent, Gent
  7. 7Gynecologic Oncology, University Hospital Leuven, Leuven
  8. 8CHIREC Cancer Institute
  9. 9Medical Oncology, Jules Bordet Institute
  10. 10Fondation contre le Cancer, Brussels
  11. 11Anatomopathology, University Hospital Leuven, Leuven
  12. 12Kom Op Tegen Kanker, Brussels, Belgium


Introduction/Background Uterine corpus cancer is the most frequent pelvic gynecological cancer in Belgium, however the adherence to the management guidelines is widely heterogeneous. In order to assess the quality of management, the EFFECT (EFFectiveness of Endometrial Cancer Treatment) project was initiated by the Anticancer Fund. Here we report the results regarding the surgical management of the patients included in EFFECT.

Methodology Patients with uterine malignant tumors diagnosed between 2012 and 2016 were registered prospectively and on a voluntary basis in an online secured database hosted by the Belgian Cancer Registry (EFFECT study). Data on pathologic assessment, preoperative management, surgery, adjuvant treatment and follow-up were collected. We present the demographic characteristics, pathological assessment and surgical management of the whole study population.

Results Overall, 4037 new cases were registered by 59 participating centers. The mean number of patients treated by each center was 65, 14 centers registered more than 100 patients during the whole period. The median patients‘ age was 69 years (range, 22–98 years). 95,5% of operated malignant tumors were carcinomas, 4,5% were sarcomas. 78% of the patients with a carcinoma and 75% of the sarcomas were FIGO stage I. 56% of operated patients were treated by minimally invasive surgery (laparoscopy or robotic-assisted laparoscopy), 36% by laparotomy and 7% by exclusive vaginal surgery. 44% of the operated patients had surgical lymph node staging (72% pelvic lymphadenectomy, 2% para-aortic lymphadenectomy, 22% pelvic and para-aortic lymphadenectomy). The median number of pelvic nodes resected was 17 (0–73) and for para-aortic nodes 11 (0–84).

Conclusion Only half of the patients with clinical stage I were operated by minimally invasive surgery, 7% of patients were operated by exclusive vaginal surgery inappropriate for fit patients. Further analysis will assess the Quality of Care and hopefully permit to improve surgical and oncologic outcomes by the feedback provided to the different centers.

Disclosure Nothing to disclose.

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