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EP1291 What factors affect quality of life in patients with gynaecoloc cancers? A prospective cohort study at the University Hospital of the West Indies
  1. N Medley,
  2. A Robinson,
  3. I Bambury and
  4. C Rattray
  1. Gynaecologic Oncology | Obstetrics and Gynaecology, University of the West Indies, Kingston, Jamaica


Introduction/Background The impact of cancer and cancer treatment on quality of life (QoL) plays an increasingly important role in management decisions in gynaecologic oncology. This is the first study in our institution looking at determinants of QOL. The aim of this study is to identify factors impacting QoL in patients newly diagnosed with endometrial, ovarian and cervical cancer and to determine the effect of treatment in these patients.

Methodology All patients newly diagnosed with ovarian, endometrial and cervical cancer were recruited from the gynaecologic oncology out-patient department between November 2018 and May 2019. Participants completed the FACT-G questionnaire at baseline, 6-weeks and 6-months after treatment. The domains assessed were physical well- being (PWB), emotional well- being (EWB) social well-being (SWB) and functional well-being (FWB).

Results A total of 112 participants were enrolled: 40 persons with cervical cancer, 39 with endometrial cancer and 33 with ovarian cancer representing 36%, 35% and 29% respectively. The mean age of the cohort is 53.7 (+15.5) years. Fifty- eight per cent of participants presented at stage one (n=65, 58.0%) and fifty-five per cent reported only mild restriction in physical activity at diagnosis. Participants had good FACT- G scores across all domains of QoL. The mean scores for PWB and EWB improved from baseline to six- weeks after treatment and then returned to basleine by six months after treatment (p=0.03). There was no statistically significant change in the SWB and FWB scores at six weeks or six months after treatment.

Conclusion Patients with cervical, endometrial and ovarian cancer have a good quality of life across all domains of physical, emotional, social and functional well-being. This is attributed to younger age, good functional status and early stage disease at diagnosis. Treatment did not significantly affect the quality of life in these women.

Disclosure Nothing to disclose

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