Introduction/Background There is limited evidence that favours the use of the sentinel lymph node (SLN) technique in ovarian cancer. A standardised approach has not been studied. The objective of the present study was to determine the safety and feasibility of the SLN technique by applying a clinical algorithm.

Methodology Twenty patients with histologically confirmed ovarian cancer were prospectively included. ^99mTc and indocyanine green were injected into the ovarian and infundibulopelvic ligament stump. An intraoperative mobile gamma camera, a gamma probe and near-infrared fluorescence imaging were used for SLN detection.

Results The SLN technique was performed in 20 patients. The SLN detection rate at both the pelvic and para-aortic region was 19/20 (95%); this value represented a 100% SLN detection rate at the pelvic and/or para-aortic region. The SLN migration and tracer distribution rates of SLN were 100% for ^99mTc + ICG, 100% for ^99mTc alone and 95% for ICG alone. The mean number of harvested SLNs was 2.2 ± 1.5 (range 0–5) nodes in the pelvic field and 3.3 ± 1.8 (range 1–7) nodes in the para-aortic region. There were no adverse events reported during surgery or the 30-day post-surgery.

Conclusion Detection of SLN in early-stage ovarian cancer appears to be a safe and feasible technique (NCT03452982).

Disclosure Nothing to disclose