Introduction/Background Vaginal malignant melaona is rare non-cutaneous melanoma. It account less than 5% of vaginal cancers and 0.5% of all malignant melanomas. I experienced 2 cases of primary malignant melanoma.

Methodology Case 1: 58 years old patient was referred due to vaginal black discoloration. She was noticed black discoloration 3 months ago at local OBGY clinical.

3 months later, local clinical doctor said black discoloration increased and recommended to our hospital. Punch biopsy was done on several black colored vaginal surface.

Case 2: 62 years old patients visited my office due to vaginal discharge. There was black discolortaion spreading whole vaginal surface including uterine cervix. Punch biopsy was done on vagina and uterine cervix.

Results I did Robot assisted radical hysterectomy with pelvic lymph node dissection. I did upper 1/3 vaginal dissection via intraperitoneal approach and via vaginal approach I did total vaginectomy. Plastic surgeon did vulvovaginal reconstruction surgery.

Conclusion 1st case there was pelvic lymph node positive and 2nd case was lymph node negative. I did adjuvant immounotherapy on 1st case patient and did not done any adjuvant therapy on 2nd patient.

Disclosure Nothing to disclose