Introduction/Background Vulval cancer is a rare malignancy, accounting for 3–5% of all cancers of female genital organs, with approximately 500 new cases diagnosed in Poland yearly. The study has been aimed at the analysis of the frequency of adverse prognostic factors in patients undergoing radical electro-surgery and groin lymphadenectomy.

Methodology A total of 28 cases have been analysed. All patients covered by the study had FIGO stage IB-III vulval cancer and were treated with radical electro-surgery and groin lymphadenectomy between March 2016 and December 2018 The patients' age ranged from 46 to 82 years old, and their eligibility for treatment was decided by a designated panel of specialists made up of gynaecologic oncologists, radiotherapy specialists and clinical oncologists. Surgical treatment consisted in radical electro-resection and groin lymphadenectomy.

Results Early recurrence was found in 6 patients (22%). 4 out of 6 patients had local vulvar recurrence, which was treated with a wide excision with a surgical margin = 1 cm. In all cases of early recurrence, the primary tumour had involved the clitoris.

The remaining 2 patients suffered from groin recurrence. In all these cases, a narrow original surgical margin ≤ 0.3 cm was determined, and the patients had post-surgically received adjuvant intensity modulated radiation therapy (IMRT) in a dose of 50 Gy/25 fr.

Conclusion 1.Adverse prognostic factors in vulval cancer patients treated with radical electro-resection surgery and groin lymphadenectomy include:

-clitoral involvement,

-narrow surgical margin ≤ 0.3 cm, the latter correlating with a higher incidence of groin recurrence.

Disclosure Nothing to disclose