EP1118 Patient-derived ovarian cancer organoids resemble clinical response to chemotherapeutics and provide insights into response mechanisms

CJ de Witte; E Stelloo; N Hami; J Espejo Valle-Inclan; K Lõhmussaar; O Kopper; C Vreuls; T Jonges; PJ van Diest; H Clevers; HJG Snippert; WP Kloosterman; RP Zweemer; PO Witteveen

doi:10.1136/ijgc-2019-ESGO.1160

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EP1118 Patient-derived ovarian cancer organoids resemble clinical response to chemotherapeutics and provide insights into response mechanisms

Authors

CJ de Witte 1Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University 2Oncode Institute PubMed articles Google scholar articles
E Stelloo 1Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University 2Oncode Institute PubMed articles Google scholar articles
N Hami 2Oncode Institute 3Molecular Cancer Research, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University PubMed articles Google scholar articles
J Espejo Valle-Inclan 1Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University 2Oncode Institute PubMed articles Google scholar articles
K Lõhmussaar 2Oncode Institute 4Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and UMC Utrecht PubMed articles Google scholar articles
O Kopper 2Oncode Institute 4Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and UMC Utrecht PubMed articles Google scholar articles
C Vreuls 5Department of Pathology, University Medical Center Utrecht, Utrecht University PubMed articles Google scholar articles
T Jonges 5Department of Pathology, University Medical Center Utrecht, Utrecht University PubMed articles Google scholar articles
PJ van Diest 5Department of Pathology, University Medical Center Utrecht, Utrecht University PubMed articles Google scholar articles
H Clevers 2Oncode Institute 4Hubrecht Institute, Royal Netherlands Academy of Arts and Sciences and UMC Utrecht 6The Netherlands Princess Máxima Center for Pediatric Oncology PubMed articles Google scholar articles
HJG Snippert 2Oncode Institute 3Molecular Cancer Research, Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University PubMed articles Google scholar articles
WP Kloosterman 1Center for Molecular Medicine, University Medical Center Utrecht, Utrecht University PubMed articles Google scholar articles
RP Zweemer 7Department of Gynaecological Oncology, Cancer Center PubMed articles Google scholar articles
PO Witteveen 8Department of Medical Oncology, Cancer Center, University Medical Center Utrecht, Utrecht University, Utrecht, The Netherlands PubMed articles Google scholar articles

Citation

de Witte C, Stelloo E, Hami N, et al

EP1118 Patient-derived ovarian cancer organoids resemble clinical response to chemotherapeutics and provide insights into response mechanisms

International Journal of Gynecologic Cancer 2019;29:A582-A583.

Publication history

First published November 1, 2019.

Online issue publication

March 03, 2020

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