Introduction/Background Obesity negatively impacts the quality of life of gynaecological cancer patients. Sexual function is an important part of woman's quality of life, however the association between Body Mass Index (BMI) and sexual functioning in gynaecological cancer patients is unclear. In addition the relationship between socioeconomic deprivation, which is linked to obesity, and sexual function is unclear.

Methodology This is a prospective cohort study on women undergoing surgery for suspected or proven gynaecological cancer between September 2014 and February 2016 in the Royal Cornwall Hospital Trust. Patients were invited to participate by completing the Female Sexual Function Index (FSFI) at three time points: pre-operative, three months post-operative and one-year post-operative. A semi-parametric model of the FSFI score was used to establish the association between BMI and sexual functioning.

Results A total of 257 patients were approached of which 166 patients were included. 52 patients (33.8%) were overweight (BMI 25–29.9 kg/m²), 44 (28.6%) were obese (BMI 30–39.9 kg/m²) and a further 20 (13.0%) morbidly obese (BMI ≥ 40 kg/m²). Overweight and obese women reported improved sexual functioning compared to normal-weight women in endometrial, ovarian and vulvar cancer. Among cervical cancer, worse sexual functioning was seen in women with an increased BMI, however this was not significant. Younger age was associated with improved sexual function and sexual functioning was better postoperatively for all patients compared to preoperatively. There was no evidence of relationship between deprivation and sexual functioning in gynaecological cancer patients.

Conclusion Higher BMI is associated with improved sexual functioning in endometrial, ovarian and vulvar cancer, however this was not seen in cervical cancer patients. There is no evidence of correlation between deprivation and sexual functioning.

Disclosure Nothing to disclose