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EP1076 Dependence between arterial hypertension and endometrial hyperplasia in pre- and postmenopausal women
  1. A Ganovska and
  2. S Kovachev
  1. Military Medical Academy, Sofia, Bulgaria


Introduction/Background Endometrial hyperplasia is a condition of the endometrium characterized by hyperplasia of the endometrial glands. According to histological morphology, the presence of atypical cells is subdivided into typical and atypical hyperplasia. Atypical hyperplasia is a premalignant condition that can progress to endometrial adenocarcinoma.

Methodology The study is one-central, retrospective over a two-year period (2017–2018), conducted at a clinic of general and oncology gynecology. The study included 308 patients with symptomatic abnormal uterine bleeding. All women were given a history of gynecological examination followed by a test sample of abrasion under short-term venous anesthesia. For arterial hypertension are taken blood pressure values exceeding 140/80 mmHg for a period of six months prior to surgery.The aim of the study is to determine the relationship between arterial hypertension and the risk of endometrial hyperplasia in pre- and postmenopausal women.

Results The average age of patients in the study was 51.1 years (24 to 87 years). In 6 (1.9%) women, arterial hypertension and atypical endometrial hyperplasia were detected. In 21 (6.8%) patients, arterial hypertension and typical endometrial hyperplasia were found, and in 7 (2.3%) endometrial carcinoma and arterial hypertension. After the statistical treatment of the results, we established a relationship between arterial hypertension and the incidence of both typical and atypical endometrial hyperplasia. We have not found a similar relationship between arterial hypertension and enometric carcinoma.

Conclusion In patients with arterial hypertension and uterine bleeding, the risk of endometrial hyperplasia is higher. Timely diagnosis of this type of pathology is necessary, which allows for timely treatment and prophylaxis for progression in endometrial cancer.

Disclosure Nothing to disclose

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