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EP1031 Ovarian high-grade sarcoma: case report and literature review
  1. S Yazdani,
  2. A Hosseini,
  3. M Abedisamakoush and
  4. M Naeimi Rad
  1. Babol University of Medical Sciences, Babol, Islamic Republic of Iran


Introduction/Background These biologic lesions are invasive and most patients were observed with metastases. Therefore, this article introduces a 42-year-old female case with a metastasis aromatic sarcoma admitted to Ayatollah Rouhani Hospital in Babol in 2017.

Methodology A 42-year-old female patient with abdominal pain and abnormal vaginal hemorrhage which had a large pelvic mass showed in CT scan with the size of 186 × 196 × 146 mm, with a compressive effect on the rectum and bladder, bilateral hydronephrosis and the involvement of brain, liver and the inguinal and pelvis lymph nodes (figures 1 and 2). In the initial tests, the hemoglobin level was 9 mg and creatinine 10 mg/dL, so she was dialyzed due to the impossibility of nephrostomy and the patient’s creatinine was decreased.

Results In the normal bimanual examination of cervix, there was a large mass in the umbilical cord with a clear compression effect on the posterior Choledosac area. The patient was underwent laparotomy operation 5 days after hospitalization, in which a large tumoral mass was observed with severe adhesion to the uterus; so part of the sigmoid colon was removed with the uterus and ovaries and colostomy was performed. There were liver metastasis and tumor invasion into the retroperitoneal area, and the Cytoreduction was performed as much as possible. The patient was admitted to the ICU after surgery and had seizure and electrolyte disturbances due to the fever resistant to drug therapy expired. In the pathology of ovarian sarcoma with IHC, Vimentine Ki67, positive CD10, IHC, AE1-AE3, negative SMA and S100 were reported.

Conclusion Ovarian sarcoma tumor is rare but highly invasive. In order to improve the survival of patients, it is necessary to find early diagnostic methods in these patients and to conduct a faster surgical operation with Cytoreduction Optimal.

Disclosure Nothing to disclose.

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