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EP937 Frailty assessment in treatment for elderly patients with ovarian cancer
  1. R Nakamura,
  2. K Takahashi,
  3. N Oshima,
  4. K Wakana and
  5. N Miyasaka
  1. Perinatal and Women’s Medicine, Tokyo Medical and Dental University, Tokyo, Japan


Introduction/Background We are faced with an increasing proportion of elderly ovarian cancer patients. It is still debating what is adequate treatment for such patients. The aim of this study was to analyze the feasibility of standard surgery and chemotherapy in the elderly ovarian cancer patients.

Methodology We evaluated 32 patients of 70 years old or older who were treated at our department between 2009 and 2017 retrospectively. Background, type of surgical procedure, complications, schedules of chemotherapy, and clinical outcome were registered.

Results The average age was 76 years old. Their median performance status (PS) is 1 (0–4). The number of patients was 17 in stage I, 4 in stage II, 8 in stage III and 3 in stage IV according to the International Federation of Gynecology and Obstetrics (FIGO). In malignant tumor, the histologic type was serous type (n=9), clear-cell type (n=4), endometrioid type (n=4), mucinous type (n=3) and other type (n=2). As the primary treatment, twenty-nine patients were performed surgery, and three received chemotherapy. Among the patients who underwent surgery, blood transfusion was needed in 28%. Ileus occurred in 13.7%. Thirteen patients received chemotherapy before or after surgery. The rate of dose reduction, treatment delay, and discontinuation were 38%, 61%, and 38%, respectively.

Conclusion Elderly patients are higher rate of advanced cancer and complications during treatment. We need a screening tool, for example CSGA (Cancer Specific Geriatric Assessment), to select adequate therapy.

Disclosure Nothing to disclose.

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