Article Text

Download PDFPDF
EP897 Clinical application of the sentinel lymph node technique in early ovarian cancer: phase II clinical trial
  1. V Lago,
  2. P Bello,
  3. B Montero,
  4. L Matute,
  5. P Padilla-Iserte,
  6. S Lopez,
  7. M Agudelo and
  8. S Domingo
  1. University Hospital La Fe, Valencia, Spain


Introduction/Background There is limited evidence favoring the use of the sentinel lymph node technique in ovarian cancer, and no standardized approach has been studied. The objective of the present pilot study and clinical trial is to determine the feasibility of the sentinel lymph node technique by applying a clinical algorithm and the use of 99mTc and indocyanine green for its detection.

Methodology Patients with confirmed ovarian cancer were included. 99mTc and indocyanine green were injected into the ovarian and infundubulo-pelvic ligament stump.

A gamma probe and near-infrared fluorescence imaging were used for sentinel lymph node detection.

Results The sentinel lymph node technique was performed in 10 patients in the pilot study and in 20 patients in the clinical trial with a detection rate in the pelvic and/or para-aortic region of 100%.

Conclusion The sentinel lymph node technique appears to be applicable in early-stage ovarian cancer with excellent detection rate. further studies are needed to establish the negative predictive value of the technique.

Disclosure Nothing to disclose.

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.