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EP878 Anastomotic bowel leakage after cytoreductive surgery in advanced epithelial ovarian cancer surgery: relation to surgical specialty and complexity score
  1. U Joneborg1,
  2. S Salehi1,
  3. H Falconer1,
  4. PJ Nilsson2 and
  5. A Flöter Rådestad1
  1. 1Division of Gynecologic Oncology
  2. 2Division of Colorectal Cancer, Karolinska University Hospital and Karolinska Institutet, Stockholm, Sweden


Introduction/Background Radical cytoreductive surgery is the most important prognostic factor for survival in women with advanced epithelial ovarian cancer (EOC). Extra-pelvic procedures, including bowel resections, are often necessary to achieve complete tumor resection. Anastomotic leakage (AL) is a severe postoperative complication with risk of perioperative death and delay in time to start of adjuvant chemotherapy. The objective of this study was to evaluate AL rates in relation to surgical specialty and complexity score.

Methodology Consecutive women with advanced EOC who underwent bowel resection as part of cytoreductive surgery at Karolinska University Hospital between 2004–2011 and 2014–2016 were identified in hospital data bases. Descriptive statistics was performed.

Results Ninety-three and 101 women were analyzed in the early (2004–2011) and late (2014–2016) cohorts respectively. Demographic data was similar between groups. Bowel surgery performed by colorectal surgeons decreased from 89% to 20% (p<0.001). The rate of upfront surgery increased from 70% to 99% (p<0.001) and surgical complexity score (SCS) from 6.3 to 9.8 (p<0.001) between the cohorts. AL decreased from 6.5% to 4% (p=0.52).

Conclusion Despite a significant increase of bowel resections performed by gynecologic oncologists, upfront surgery and SCS, there was no increase in AL rate. Bowel surgery can safely be performed by trained gynecological oncologists.

Disclosure Nothing to disclose.

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