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EP669 Fertility sparing surgery for borderline ovarian brenner tumour: a literature review
  1. G Garofalo,
  2. D Bucella,
  3. D Thomas and
  4. F Buxant
  1. Hôpital d’Ixelles, Université Libre de Bruxelles, Bruxelles, Belgium


Introduction/Background Borderline ovarian Brenner tumours (BOBTs) represent less than 0,01% of all ovarian cancers with good prognosis. Average age at presentation is 50. We revised the literature to improve our counselling.

Methodology We reviewed three databases (Medline, LILACS, Central Cochrane Library) and found six case series and ten case reports with a total number of 58 cases.

Results Four cases are reported under 40 years. Only two cases of fertility sparing surgery (FSS) by unilateral salpingo-oophorectomy were performed, and only one case of spontaneous pregnancy is described (table 1). In this last case, BOBTs appeared at ultrasound as a four centimetres multilocular anechoic cyst with a papillary projection. Table 2 shows the good prognosis of this tumour: only two cases of recurrence were reported.

Conclusion Good prognosis of BOBTs supports FSS. However, literature is scarce on BOBTs due to its low prevalence. The prevalence is even lesser in young women which explains the only two cases of FSS. For serous and mucinous borderline tumours, a bilateral cystectomy for bilateral tumours or unilateral salpingo-oophorectomy (or even cystectomy) for unilateral tumours is widely accepted as the treatment to propose to patients willing to conceive. The recurrence rate is higher but the overall survival doesn’t change. In these cases, completion surgery is a controversial point. Follow up is commonly intensified in first two years. The same aptitude can be proposed to BOBTs even in the absence of strong studies.

Disclosure Nothing to disclose.

Abstract EP669 Table 1

Overall BOBTs, Fertility Sparing Surgery and subsequent pregnancy

Abstract EP669 Table 2

Overall BOBTs and their recurrences

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