Introduction/Background Reproductive health in Uzbekistan is one of the priorities way of medicine. Currently, carrying out IVF in patients with uterine myoma is relevant in practical medicine.

Methodology Studied 86 patients with IVF and uterine myoma. Women were divided into 2 groups: the first was 45 patients with intramural localization of the node, which deformed the uterine cavity with a diameter of not more than 3 cm; the second is 41 patients with a myoma node that does not deform the uterine cavity with a diameter of up to 3 cm.

Results In patients of 1 group, 6 (13,3%) women had one IVF attempt, only three women (6,7%) had a uterine pregnancy. Further observation showed that two pregnant women had a spontaneous miscarriage, one pregnancy ended in premature labor in the period of 35–36 weeks. Thus, the pregnancy rate for one attempt in patients with an intramural node with a diameter of not more than 3 cm, deforming the uterine cavity, was 13,3%. Of the 41 women with a myoma node with a diameter of up to 3 cm, which do not deform the uterine cavity, pregnancy as a result of IVF occurred in 15 (36,6%) patients. In one case (2,4%), it was ectopic. In two cases (4,9%), spontaneous miscarriages occurred in the first trimester of pregnancy.

Conclusion The node with a diameter of up to 3 cm, which does not deform the uterine cavity, does not adversely affect the performance of the IVF procedure and was 36,6%. The node with a diameter of up to 3 cm, which deforms the uterine cavity, significantly reduces the effectiveness of IVF by 2,7 times and implies surgical treatment before the IVF program.

Disclosure Nothing to disclose.