Introduction/Background Endometrial cancer is estimated to be most common female cancer. Among other predictive factors, inflammation biomarkers resulting from white blood cell and platelet counts ratios have been introduced in the assessment of endometrial cancer.
Methodology Preoperative NMR, LMR, NPR, LPR and MPR ratios in 154 patients of the gynecological department of Metaxa Memorial Cancer Hospital were calculated.
Results PLR was significantly different between women with negative and women with positive lymph nodes, women with mucinous histology type and those with serous histology type and between patients with stage I and patients with stage III disease. MPR was significantly different between women with stage I and women with stage III too but also between women with stage III and women with stage IV disease as well as patients with positive and patients with negative lymph nodes. LMR was found to be significantly different between patients with negative and patients with positive disease in the upper abdomen, between endometrioid and serous type of histology, grade 1 and grade 3 disease, women with stage I and women with stage IV and between women with stage II and women with stage IV. NPR was significantly different between women with stage I and women with stage III cancer and between women with stage III and women with stage IV cancer and patients with negative and patients with positive lymph nodes. Finally, NLR was significantly different between women with mucinous histology and those with serous histology and between women with stage I and stage IV.
Conclusion NPR and MPR were associated with the nodal status while NLR and PLR were correlated with serous or mucinous histology. Upper abdomen metastases and endometrioid histology seem to have an effect on LMR and all of the profiles were found to be affected by the stage and the grade of the tumor.
Disclosure Nothing to disclose.
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