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EP579 Our experience with sentinel lymph node mapping in endometrial cancer
  1. M Miro Matos,
  2. C Millan Lomana,
  3. A Vegas Carrillo de Albornoz,
  4. I López Carrasco,
  5. M Perez Requena,
  6. N Montero Pastor and
  7. E Moratalla Bartolomé
  1. HM Hospitales—Centro Integral Oncológico Hospital de Madrid Clara Campal, Madrid, Spain


Introduction/Background Endometrial cancer is the most common gynecologic malignancy in Spain. Surgical evaluation of the lymph nodes is important in these patients. Traditionally, lymph node assesment required complete pelvic and paraaortic lymphadenectomy. Nowadays, Sentinel lymph node (SLN) mapping is gaining wide difussion with the goal of reducing the high morbidity associated with complete lymphadenectomy. The detection of nodal metastasis is a good marker of poor prognosis and will influence the decision of giving adyuvant therapy.

Methodology Patients were surgically staged by two different surgeons in the same institution. The cohort includes patients diagnosed of endometrial cancer at early- stages from 2017–2019 who underwent a SLN mapping. Indocyanine green (ICG), an methylene Blue in some cases, was injected into the uterine cervix at 3 and 9 o’clock. Fluorescence Imaging was used to visualize ICG tracer.

Results Twenty patients were enrolled. The median age was 61.35 years. The mean body-mass index(BMI) was 28.84. The overall detection rate (DR) of SLN mapping was 80% (16/20) with a 55% (11/20) bilateral detection. The addition of methylene blue to ICG did not increase the DR. No nodal metastasis were found. Five complete pelvic lymphadenectomies and three para-aortic were perfomed laparoscopically when >50% myometrial infiltration was identified. Lymph node macrometastasis were found in 20% (1/5).

Conclusion Further studies are needed to standarize the SNL mapping as an alternative to traditional lymphadenectomy. Our results are similar to the ones published in the literature. Nevertheless, much larger sample size is needed to to draw any relevant conclusions.

Disclosure Nothing to disclose.

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