Article Text

Download PDFPDF
EP477 Laparoscopic versus abdominal surgery for 70-years and older women with endometrial cancer
  1. I Berlev,
  2. Y Trifanov,
  3. Z Ibragimov,
  4. O Smirnova,
  5. K Guseinov,
  6. H Mkrtchyan,
  7. N Mikaya,
  8. A Sidoruk,
  9. E Ulrikh and
  10. A Urmancheeva
  1. Oncogynecology, N.N. Petrov National Medical Research Center of Oncology, Saint-Petersburg, Russian Federation


Introduction/Background Endometrial cancer (EC) is the most common gynecological malignancy in developed countries. The complexity of treating patients with EC older than 70 years is numerous associated diseases, and high risk of intra- and postoperative complications. Our research compares results of surgical treatment EC performed laparoscopic and abdominal approach.

Methodology Laparoscopic and abdominal EC operations were collected from 2010–2017. Data included weight, body mass index (BMI), operative time, estimated blood loss, number of removed lymph nodes, hospital stay were collected and compared. Postoperative complications were graded according to the Clavien-Dindo Classification. Survival outcomes within the first 3-years were analyzed using the Kaplan-Meier method.

Results During the study period, there were 80 elderly women, who underwent surgery with the laparoscopy and 80 women, who underwent traditional abdominal approach. Total hysterectomy with pelvic lymph-node dissection perfomed more than 70% of cases in both groups. Patients undergoing laparoscopy experienced similar operative time (p>0.05), lower blood loss (p<0.05), and shorter hospital stay (p<0.05) than patients undergoing open surgery. Laparoscopy is related to a lower rated postoperative complications (p<0.05) and didn't have more than grade II complication. The route of surgical approaches did not influence the 3-year disease-free (P=0.84, log-rank test) and overall (P=0.87, log-rank test) survivals.

Conclusion Our data suggest laparoscopy is a safe and effective approach in treatment of endometrial cancer in women aged 70 years or older. Laparoscopy improves peri- and postoperative outcomes without any influence to long-term outcomes compare to open abdominal surgery.

Disclosure Nothing to disclose.

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.