Introduction/Background To evaluate the feasibility and safety of laparoscopic nerve-sparing radical hysterectomy (LNRH) for locally advanced cervical cancer (LACC).

Methodology 14 patients with stage IB3 and IIA cervical cancer were treated surgically with laparoscopic nerve sparing Radical Hysterectomy without Uterine manipulator at St. Luke's hospital in Thessaloniki, Greece and at Mother and Child Medical Centre in Nikosia, Cyprus. Preoperatively all patients had undergone clinical staging and MRI for the evaluation of lymph node status.

Results 7 patients with stage IB3 and 7 patients with stage IIA disease underwent laparoscopic radical nerve sparing radical hysterectomy without uterine manipulator. We performed in all patients pelvic lymphadenectomy and in 9 cases we continued with para - aortic lymphadenectomy. No patient had any major complication and the mean blood loss was 265 ml (140–300 ml). Patients were mobilized the first postoperative day and the catheter was removed on the third postoperative day with residual urine volume less than 50 ml. All patients underwent adjuvant Chemo - Radio therapy. The mean follow-up is 44 months (6–73). The recurrence rate was 7% (1 pt) and the mortality rate was 0% (0pt).

Conclusion Laparoscopic nerve sparing radical Hysterectomy without uterine manipulator is feasible and safe in patients with advanced cervical cancer. It offers oncological safety and the advantages of laparoscopy and nerve sparing technique. Furthermore the patients are able to receive adjuvant therapy directly without losing valuable time in postoperative recuperation.

Disclosure Nothing to disclose.