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EP417 Trends in the incidence of carcinoma in situ and cervical cancer in ukraine
  1. N Tsip1,
  2. Y Mykhaylovich1,
  3. Z Fedorenko1,
  4. O Sumkina1,
  5. L Kuzenko1 and
  6. MA Khalfalla2
  1. 1National Cancer Institute
  2. 2Shupyk National Medical Academy of Postgraduate Education, Kyiv, Ukraine

Abstract

Introduction/Background To study the dynamics of the incidence of carcinoma in situ of the cervix (code MKH-10 D06), compared with cervical cancer (C53) in Ukraine during the period from 2006 to 2016.

Methodology The methods of statistical analysis used in descriptive oncoepidemiology were applied. A cohort of patients with cervical cancer included 56579 cases; a cohort of patients with carcinoma in situ - 12387 cases.

Calculation of incidence rates was carried out on the basis of 100 thousand of the population, as well as standardized according to the world standard updated incidence rates of the population for 2006–2016.

The data processing was carried out using the programs of the information system of the National Cancer Registry of Ukraine.

Results The incidence rate of CC remains virtually unchanged over the past 10 years (about 20 cases per 100,000 female population). However, there was a redistribution of the incidence of CC depicting its increase in women of reproductive age and reduction in women after 50 years (figure 1).

Meanwhile, incidence of cancer in situ has a steady tendency to increase (from 3.5 0/0000 in 2006 to 5.8 0/0000 in 2016).

Despite the increased number of cases of carcinoma in situ, the C53/D06 ratio remains unsatisfactory: it varies from 0.04 to 0.74 and averages 0.23 in Ukraine.

Conclusion The problem of prompt diagnosis and treatment of carcinoma in situ and cervical cancer acquires not only medical and biological but also socioeconomic value, since the incidence of this pathology reaches peak values in women of reproductive age, which directly affects the labor and demographic potential of the population in Ukraine.

The way to solve this problem is to strengthen the material and technical base and implement the State Program ‘Cervical Cancer Screening’

Disclosure Nothing to disclose.

Abstract EP417 Figure 1

Age-related rates of the incidence of cervical cancer and carcinoma in situ in Ukraine

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