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EP414 Completion hysterectomy after radiotherapy in advanced stages of cervical cancers
  1. A Touimi Benjelloun,
  2. Z Edderdabi,
  3. M Moutahir,
  4. M Benhessou,
  5. M Ennachit and
  6. M Elkarroumi
  1. Centre Mohamed IV de Chirurgie Oncogynecologique, Hassan II University/Faculté de Medecine et de Pharmacie, Casablanca, Morocco

Abstract

Introduction/Background The standard treatment of locally advanced cervical cancer is the combination of a concurrent radiochemotherapy (RCC) ± brachytherapy. Completion hysterectomy remains a therapeutic option, but its place is debated. This surgery is still contraversial because of its morbidity and nonproven benefits. The aime of this study was to evaluate the morbidity, the per and post operative complications and their risk factors, also to determine the post therapeutic prognosis and its factors in disease free survival and overall survival at 2 years.

Methodology An observational retrospective monocentric cohort concerning 82 patients cared for cervical cancer stage IB2-IV between 2016–2017 was conducted. All patients included in this study were treated with RCC ± brachytherapy followed by a completion surgery. All surgery complications and morbidity rate were registred. All risk and prognosis factors were studied. We analyzied the post operative prognosis.

Results In this study, we had patients with epidermoide carcinoma in 93.90% and adenocaricnoma in 4.88%, with advanced stages, IIB (73.17%), IIIB (9.75%), IIA (12.19%), IB2 (1.22%) and IVA (1.22%). All patients recieved radiotherapy with 93.90% of patientes recieving between 41 and 50 Gy. 33 patients (40.24%) recieved a brachytherapy. 74 patientes (90.24%) recieved a chemotherapy (concomitant for 71 patients.

The radicality of the surgery and favoring the laparotomy weren’t statistically associated with a higher rate of complications. 70.73% of patients presented a complete response to the treatment. The impact of completion surgery on the quality of life and the sexual and couple’s life after the treatment wasn’t verified due to a lack of information.

Conclusion Our study found a miner and acceptable rate of per and postoperative complications with no gravity. Finally, this study has found important benefits of completion surgery on complete response and survival rate with acceptable rate of complications.

Disclosure Nothing to disclose.

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