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EP390 Open radical hysterectomy for early cancer cervix – 10 years’ experience from a tertiary cancer centre
  1. PN Rema
  1. Division of Gynaecological Oncology, Department of Surgical Services, Regional Cancer Centre, Thiruvananthapuram, India

Abstract

Introduction/Background Carcinoma cervix is the most common cause of cancer related death among women in developing countries. Early cervical cancer is surgically treated by radical hysterectomy and bilateral pelvic lymph node dissection. Recent studies have highlighted the advantage of open radical hysterectomy over minimally invasive surgery in better patient survival. The aim of the study was to assess the survival outcome and post operative morbidity of early cervical cancer patients treated by open radical hysterectomy.

Methodology Between January 2008 and December 2018, seventy eight cases of early cancer cervix who underwent open radical hysterectomy at our centre, comprised the study group. After obtaining institutional review board approval the case records of these patients were analyzed in detail for clinical and histopathologic details, surgical parameters, post operative morbidity, details of adjuvant treatment and disease status on follow up. All patients were clinically staged according to the International Federation of Gynecology and Obstetrics (FIGO) 2009 staging system. Patients were followed up till February 2019. Survival analysis was done using the Kaplan-Meier curve.

Results The mean age of presentation was 49.5 years (range 21–72years). The histological type was squamous in 52 patients, adenocarcinoma in 22 and adenosquamous in 4. Most patients belonged to FIGO stage IB1 (70.5%) followed by stage IIA1 (11.5%), Stage 1B2 (9%)stage IA2 (6.4%%) and IA1 with LVSI (2.4%). The most common post-op complication was bladder dysfunction, which was seen in 15.4% followed by urinary tract infection in 9%. 52.6% received adjuvant chemoradiation. 5 patients had locoregional recurrence and three patients had distant metastasis. 5-Year disease free survival was 88.1% and overall 5 year survival was 94.6%.

Conclusion This study suggests that open radical hysterectomy has good survival outcome in early cervical carcinoma and with minimal post operative morbidity.

Disclosure Nothing to disclose.

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