Introduction/Background The purpose of the study is to determine if superb microvascular imaging (SMI) and shear wave elastography (SWE) can be used for the early diagnosis of uterine cervical intraepithelial neoplasia and cancer.

Methodology A case-control study was carried out in St. Marianna University School of Medicine Hospital between April 2017 and January 2018 on patients with uterine cervical dysplasia and uterine cervical cancer. Seventeen controls with eight subjects were investigated. An evaluation using SMI and SWE was conducted in addition to the conventional ultrasonic tomography and color doppler tests before or after the treatment. The colored races plastic intensity in the SMI was evaluated for three phases, strong, mediate, weak, and the blood flow rate was measured. The SWE was measured at several locations and the mean value was used as signal intensity.

Results The target breakdown was one patient with uterine cervical cancer and seven patients with high-grade squamous intraepithelial lesions. For the subject and control cases, the intensity of the conventional colored races plastic was 6% vs. 0% (n.s.), and 94% vs. 100% for strong and weak phase, respectively. While for the control the measure, it was 39% vs. 0% and 61% vs. 100% for strong and weak phase, respectively. In addition, one patient with uterine cervical cancer exhibited a strong phase. The SWE evaluation of the uterine cervical hardness resulted in SWE level of 4.4±1.2, 2.2±0.3 for case and control, respectively (p<0.01).

Conclusion An evaluation using SMI and SWE utility suggested the identification of histologic changes such as minute vascular hyperplasia or malignant transformation of the uterine cervical lesion.

Disclosure Nothing to disclose.