Introduction/Background Despite uterine prolapse being a common condition in women, the coexistence of cervical cancer and uterine prolapse is extremely rare. There is no reported incidence, but the available information suggests that the incidence of cervical cancer among those with procidentia is between 0.14% and 1%.

Methodology 86-year-old woman admitted to our Hospital in a condition of a huge, irreducible uterovaginal procidentia with a vegetative and ulcerated lesion on which biopsy is performed; histological examination: squamous carcinoma. Total vaginal hysterectomy with bilateral bilateral salpingo-oophorectomy and total colpectomy were performed.

Results The histopathology revealed a squamous cell carcinoma of the uterine cervix 11.5 cm in size, stage IIA2 G3.

Conclusion The coexistence of cervical cancer and pelvic organ prolapse is extremely rare and the best treatment is unclear. A systematic review of the literature suggest that the prognosis following surgery-based treatment of cervical cancer patients with complete uterine prolapse may be favorable, and thus the recommended treatment option should be based on the surgeon’s preference, patient and tumor factors, and consideration of medical comorbidities.

Conclusion: surgical approach needs to be considered in women with cervical cancer complicated by complete uterine prolapse if the patient‘s condition and medical comorbidity are not limitations to surgery.

Disclosure Nothing to disclose.