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EP298 Nerve-sparing versus non-nerve-sparing radical hysterectomy: surgical and long-term oncological outcomes
  1. NR Gómez-Hidalgo1,
  2. A Gil-Moreno1,
  3. M Carbonell Socias1,
  4. S Salicrú2,
  5. M Bradbury2,
  6. A García3,
  7. R Vergés4,
  8. O Puig Puig1,
  9. JL Sánchez-Iglesias1,
  10. S Cabrera-Diaz1,
  11. J De la Torre1,
  12. A Pérez Benavente1,
  13. J Magriña5 and
  14. B Díaz-Feijoo1
  1. 1Department of Gynecology Oncology
  2. 2Department of Gynecology
  3. 3Department of Pathology
  4. 4Radiotherapy Department, Vall d’Hebron University Hospital, Barcelona, Spain
  5. 5Department of Medical and Surgical Gynecology, Mayo Clinic Hospital, Phoenix, AZ, USA


Introduction/Background There are controversies regarding the long-term oncological safety of preservation of pelvic innervation during radical hysterectomy (RH). This study aimed to analyze the feasibility and safety of nerve-sparing radical hysterectomy (NSRH) for cervical cancer compared with non-NSRH following 17 years of experience in a tertiary cancer referral center.

Methodology Between May 1999 and June 2016, all patients who underwent RH for cervical cancer were followed-up prospectively. Comparison analyses regarding surgical outcomes, complications, overall survival (OS), disease-free survival (DFS), and cancer-specific survival (CSS) were performed between patients treated with NSRH and non-NSRH.

Results A total of 188 patients were included (113 non-NSRH and 75 NSRH). The median follow-up was 112 months. Estimated blood loss and hospital stay were all significantly lower in the NSRH group. Overall intraoperative complication rate (p=0.02) and need for transfusion (p=0.016) were lower in the NSRH group. There were no differences in the median operation time, OS, DFS, CSS, or recurrence rates between the NSRH and non-NSRH group.

Conclusion Our study provides a wide perspective on the developments of nerve-sparing procedures for the management of women with early-stage cervical cancer. Our results suggest that NSRH is a feasible and safe procedure, with reduced morbidity outcomes.

Disclosure Nothing to disclose.

Abstract EP298 Figure 1

Nerve Sparing Technique: Key steps

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